Microbes in Industry

"We are guiding innovation in microbial fermentation with a rational and quantitative economic and environmental impact assessment."

 

| Sumesh Sukumara, DTU Biosustain

 

 

"In collaboration with DTU Bioengineering and DTU Biosustain, we work on scale-up/scale-down and bioprocess engineering using E. coli, P. putida, P. pastoris."

 

| John Woodley, DTU Chemical Engineering

 

 

"The group focuses on metabolic engineering of yeast cell factories for biosustainable production of chemicals from renewable feedstocks."

 

| Irina Borodina, DTU Biosustain

 

 

"I am working on process modeling and control, circular bio-economy and technology development, biological nutrient removal, biofilm, membrane aerated bioreactor, sedimentation and filamentous bulking, carbon and nutrient recovery, micro-pollutant biodegradation, green microalgae, microbial protein, bio-electrochemistry and anaerobic digestion."

 

|Borja Valverde-Pérez, DTU Environment

 

 

"I study microbial communities and processes in the aquaculture environments, aiming to optimize microbial-driven nutrient removal processes and to control unwanted microbial processes to ensure stable and sustainable fish production."

 

| Sanni-Leea Aalto, DTU Aqua

  

 

"I work with Lactic Acid Bacteria (LAB) and other food microorganisms. I am interested in optimizing food fermentations and using safe bacteria for production of valuable ingredients, e.g., from food waste. Furthermore, I am interested in using LAB to prevent growth of pathogens and food spoilage microorganisms, including fungi."

 

| Christian Solem, DTU Food

                         

 

"In my group, we use microorganisms to convert biomass (agricultural residues, agro-industrial wastes and side streams, food wastes, wood, plants and seaweeds) into chemicals, food ingredients, biofuels and high-value compounds. We develop robust strains of bacteria and non-conventional yeasts to efficiently convert sugars from complex media such as biomass hydrolysates. We also investigate the physiology of the microorganisms under different stress conditions and correlate it with their performance to grow/produce to develop and predict more efficient biomanufacturing processes."

 

| Solange Mussatto, DTU Bioengineering

 

 

"My research is mainly focused at developing a better understanding of the interactions between microbes and bioreactors, aiming in the end at obtaining a better efficiency of bio-based production processes."

 

| Krist Gernaey, DTU Chemical Engineering

 

                         

"Our research is focused on deciphering the molecular pathways and engineering the biosynthesis of natural products by combining genetic, biochemical and bioinformatics methods. We are a pioneer in developing software for the automated genome mining (CLUSEAN, antiSMASH, antiSMASH-DB) and analysis of secondary metabolite biosynthetic pathways. Our group was able to firstly elucidate the biosynthetic pathways of the elfamycin family of antibiotics and is deeply involved in developing CRISPR-based metabolic engineering tools for actinomycetes."

 

| Tilmann Weber, DTU Biosustain

 

 

"I am interested in microbiomes in recirculating aquaculture systems, including the microbiome and its association in (infectious) diseases in fish."

 

| Argelia Cuenca, DTU Aqua

 

 

"We use the theory of evolution as a framework for discovery and engineering specialized metabolites from Fungi and Bacteria."

 

| Pablo Cruz-Morales, DTU Biosustain          

 

 

"We are providing access to laboratory facilities, including GMO, MultiLab and Chemistry, manned with skilled technicians for supporting student and research startups within the 'wet'-areas at DTU."

 

| Kristine Garde, DTU Skylab

 

 

"My research interests include: Data science, machine learning, statistical learning, spectral image analysis, pattern recognition, dimension reduction, outlier detection; within industrial and educational applications."

 

| Line Clemmensen, DTU Compute

 

 

"Our research includes in silico identification of gut bacteria utilizing dietary fibers (e.g. alginate, resistant starch, plant cell wall polysaccharides) and discovery, production as well as characterization of structure function relationships of the involved bacterial enzymes. We are also interested in microbial consortia from various environments."

 

| Birte Svensson, DTU Bioengineering          

 

 

"Our research is focused on revealing regulatory paradigms in bacterial metabolism and stress response, such as Regulation of nucleotide biosynthesis in gram-positive bacteria, Stringent response in bacteria, Analysis and simulation of the decision process by bacteriophage epigenetic switches, and Phage therapy."

 

| Mogens Kilstrup, DTU Bioengineering

 

 

"In a circular economy era, biomass and waste processing technologies for sustainable production of chemicals and fuels are of high importance. Processes are developed and tested initially at laboratory scale and then at pilot scale. Our research work is performed in: Reactor fermentations, Anaerobic digestion, Industrial and municipal wastewater valorization, Waste plastic depolymerization and monomers purification, Equipment design for pre-treatment of biomass, Upstream and downstream processing of biomass effluents, Up-scaling of biotechnological processes, Mathematical simulation of bioprocesses."

 

| Ioannis Skiadas, DTU Chemical Engineering         

 

 

"May main research areas include Aquaculture, Microbial water quality, Biofiltration, and Disinfection."

 

| Lars-Flemming Pedersen, DTU Aqua          

 

 

"Our research focuses on engineering bacteria for sustainable production of chemicals that cannot be easily produced or cannot be produced, as of today, biologically. We work both on individual-species cultures as well as in bacterial communities."

 

| Pablo Ivan Nikel, DTU Biosustain                

 

 

"My focus is on anaerobic bacteria and archaea to develop and design bio(process) to produce metabolites of industrial importance."

 

|Merlin Alvarado Morales, DTU Chemical Engineering

 

 

"My research is focused on microbial food cultures for food fermentation, involving lactic acid bacteria. We investigate fermentation of bovine milk, camel milk, and plant-based fermentations. Particular focus is given to the proteolytic system and the specificity of the cell envelope proteinase. Identification of peptides derived from food proteins with potential use as functional food ingredients is central in this research."

 

| Egon Bech Hansen, DTU Food

 

 

"My research involves the development of a data focused biofoundry. Furthermore, we are creating a C1 Metabolic Atlas to capture the full range of natural C1 metabolism as a basis to engineer synthetic C1 metabolism. In addition, we work on viral vector production."

 

| Lars Keld Nielsen, DTU Biosustain

 

 

"We investigate non-conventional yeasts to develop better microbial cell factories for industrial production of high-value products from complex feedstocks such as waste-streams and salty hydrolizates.  We also investigate fundamental metabolism of yeasts to better understand stress responses associated to recombinant protein production (enzymes and biotherapeutics peptides), through combined multi-omics analyses and systems biology approaches."

 

| José Luis Martínez, DTU Bioengineering 

 

 

"The purpose of my research within Biorefinery Conversions is to create new knowledge for development of innovative and cost-efficient processes for production of fuels, chemicals and materials from biomasses, industrial effluents and industrial off-gases including carbon dioxide. Valorization of renewable resources, i.e. residual biomasses, as well as undesirable by-products of industrial activities such as liquid and solid effluents, carbon monoxide and carbon dioxide, as feedstocks for production of valuable organic molecules can greatly contribute to sustainable societies and limit greenhouse gases emissions."

 

| Hariklia Gavala, DTU Chemical Engineering

 

 

"My research involves the development of nanobodies against pathogens such as gastrointestinal and plant pathogens."

 

| Andreas Laustsen, DTU Bioengineering

 

 

"We are working on the data-driven discovery of new bioactive natural products from various microbes, especially Actinomycetes."

 

| Pep Charusanti, DTU Biosustain

 

                         

"I study bacterial eco-physiology and biotechnology and focus on aquatic bacteria (freshwater and marine). We aimed at two goals: to control, i.e., kill or inhibit disease-promoting bacteria, and to enable biotechnological use of bacteria. I am particularly interested in microbial secondary metabolites, their natural functions and biotechnological application."

 

| Lone Gram, DTU Bioengineering

 

 

"We are interested in signaling and regulation in bacterial cells, focusing in particular on regulatory phenomena based on protein phosphorylation. Most of our research activities are carried out on Bacillus subtilis. Our laboratory specializes in bacterial protein-tyrosine kinases (BY-kinases), serine/threonine kinases of the Hanks-family, phosphoproteomics other “omics” approaches aiming at global studies of the phosphorylation-based regulatory networks in both model and pathogenic bacteria."

 

| Ivan Mijakovic, DTU Biosustain